Changing trends in the incidence of thyroid cancer in the United States
Luc Morris, Michael Tuttle, Louise Davies
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The incidence of thyroid cancer in the United States has tripled in 30 years, rising rapidly since the 1990s. This substantial increase, chiefly comprising small papillary cancers, has been attributed to widespread diagnosis of subclinical disease. Autopsy studies show a sizeable prevalence (5%-30%) of clinically occult thyroid cancer in asymptomatic persons. The rising diagnosis of thyroid cancer has been linked to increasing health care utilization and imaging practices, which have led to the increased discovery of small papillary thyroid cancers, which generally exhibit indolent behavior.